Ana Lazarević took her first steps in volleyball in 2005, in the Academy of Srbijanka of Valjevo, a club of her hometown.

In 2012, she decided to leave her homeland and travel to Turkey for Beşiktaş JK, but she remained there for just one season.

In 2013, Ana Lazarević was signed by ASPTT Mulhouse, a team of the town with the same name in France, where she remained for two years.

With ASPTT Mulhouse she was awarded as Best Receiver in the 2014 edition of CEV Women's Challenge Cup, in the third place of her team in that year's competition.

[6] In May 2021, after one year of absence due to pregnancy, she returned to Serbia and signed for OK Crvena Zvezda, club that she supports since childhood.