Her mother, People's Artist of Russia[5] Valentina Borisovna Zavorotnyuk, worked in the Astrakhan Youth Theatre.

Zavorotnyuk received dance and acting lessons at the Moscow Art Theatre.

After graduating from the Moscow Art Theatre School in 1993, she became an actress under the direction of Oleg Tabakov.

[9][10] On 22 September 2008, she married figure skater Peter Tchernyshev at the Foros Church in Crimea.

[13] In September 2019, Zavorotnyuk was reported to have been diagnosed with brain cancer stage IV around the time of giving birth to her daughter, Mila, in October 2018,[14] with rumours of her diagnosis dating back as early as August 2019 when fans had noticed a scar on her neck which, as was theorised, might suggest a biopsy to test for cancer.