The Anatolian Express (Turkish: Anadolu Ekspresi, French: Anatolie Express) was one of the four direct train services operating between Istanbul and Ankara.

The train was an overnight train consisting of eight sleeping cars and one dining car.

The train was operated by the CIWL from 1927 to 1950.

From 1950 on, TCDD operates the train.

The Anatolian Express runs every night from both termini.