During his engagement at the Tallinn City Theatre Ermel has appeared in over thirty roles in productions of works by such varied international authors and playwrights as: Shakespeare, Ibsen, Dostoyevsky, Yeats, Evelyn Waugh, Anton Chekhov, Thomas Mann, and Mark Twain, among others.

Roles in productions of works by Estonian authors and playwrights include those of: Paavo Piik, Jaan Tätte, A. H. Tammsaare, Arthur Valdes, and Eduard Vilde, among several others.

[6][7] In 2013, Andero Ermel voiced the character of Guard in the Mait Laas directed 3D animated opera film Lisa Limone ja Maroc Orange: Tormakas armulugu; a social critique of African illegal immigrants fleeing to Europe and focusing on Maroc, a refugee boy who is an orange who falls in love with local lemon girl Lisa.

[8] In 2013, he voiced both the speaking and singing role of Hans in the American Disney animated musical fantasy film Frozen (retitled in Estonian as Lumekuninganna ja igavene talv).

[10] In 2022, he appeared as the character Freisinck in the Elmo Nüganen directed historical thriller-mystery Melchior the Apothecary for Taska Film, based on the novel series of the same name by Indrek Hargla.

[11] Anero Ermel's television debut was in the 1998 Vilja Palm directed Eesti Televisioon (ETV) teleplay Koor minu kohvis, which was adapted from the Dennis Potter penned Cream in My Coffee.

Ermel's impersonations included Hardi Volmer, Amanda Lear, Marko Matvere, Kurt Cobain of Nirvana, James Blunt, and Freddie Mercury of Queen, among others.