He began his career in 1993, and played in Brazil for clubs including São Paulo, Corinthians, Cruzeiro, Fluminense.

He relocated to Europe 2001 and subsequently played in Spain for Tenerife, and in France for Marseille, Paris Saint-Germain and Ajaccio.

He won the CONMEBOL Supercup, Copa Libertadores and Intercontinental Cup in 1993, two Recopa in 1993 and 1994, and São Paulo State Championship in 1997.

André Luiz signed with San Jose Earthquakes of Major League Soccer on 31 July 2009.

André Luiz played 19 matches and scored two goals for the Brazilian team.