1451, the son of Richard d'Espinay (chamberlain to Francis II of Brittany) and Beatrix de Montauban.
[1] On October 1, 1488, he was named Archbishop of Lyon, occupying that see until his death, while also retaining the metropolitan see of Bordeaux.
[1] He received the red hat and the titular church of San Martino ai Monti on March 23, 1489.
[1] He returned to the Kingdom of France in 1490, becoming commendatory abbot of Holy Cross Abbey, Bordeaux, an office he held until 1499.
[1] As such, the cardinal accompanied Charles VIII on his campaigns during the Italian War of 1494–1498, and was close to the king during the 1495 Battle of Fornovo.