She was awarded a Ph.D. in 1962 at University of Paris under the supervision of Gustave Choquet.

Her thesis was entitled Différentiabilité dans les espaces localement convexes.

[4] Ehresmann has published over a hundred works on Analysis (Differential Calculus and Infinite-dimensional Distributions, Guiding Systems and Optimization Problems), Category Theory (with her husband, Charles Ehresmann: sketches and internal categories, multiple categories, closed monoidal structures) and the modeling of complex autonomous systems (Memory Scalable Systems, including the MENS model for neuro-cognitive systems).

Based on a theory of 'dynamic' categories, evolving memory systems can analyze complexity, emergence and self-organization.

She is the director of the mathematical journal Cahiers de Topologie et Géométrie Différentielle Catégoriques.