"[7] Molina Enríquez is best known for publishing Los Grandes Problemas Nacionales (The Great National Problems) in 1909,[8] a book highly critical of the Porfirio Díaz government.
Molina Enríquez was arrested by the government of Francisco León de la Barra on August 25, 1911 for publishing the document, which has later been described as highly influential on the eve of the Mexican Revolution.
"[12] Certain prominent personalities within the Mexican liberal tradition such as Melchor Ocampo, Ignacio Ramírez, Ponciano Arriaga, José María del Castillo Velasco, and Isidoro Olvera had always had a "social" element to their liberalism inspired by French radicalism and utopian socialism, and this strand of thought influenced Molina Enríquez and other participants in the Mexican Revolution.
In order to resolve the suffering of the indigenous people, and create equality, Molina Enríquez believed they had to be integrated into the national state, this idea would be central to the indigenist movement when it went international.
Molina Enríquez would eventually go on to be a key adviser to the committee which drafted article 27 of the Mexican Constitution and a member of the National Agrarian Commission.