He then joined the royal Spanish Navy, sailed to the Moluccas, the Philippines and other islands, and was appointed a captain (Capitán de navío), rising to the rank of "Admiral" (Almirante) of the South Sea (Pacific Ocean).
[10][11][12] On 22 February Villegas decided to immediately leave Pampatar with reinforcements of 20 soldiers and 12 Waikerí bowmen under his command to engage the Dutch troops at Santiago.
On 30 November 1622, a fleet of 43 Dutch ships attacked Araya to halt construction of the Spanish fortress and seize the peninsula.
[15] On June 23, 1630, Andrés Rodríguez de Villegas was appointed governor of La Florida, a position he held until September 21, 1631[16] (however, Amy Bushnell says his term ended in July 1631) when he died in office.
He was replaced by co-interim governors Nicolas Ponce de Leon, the provincial royal accountant (contador), and Sergeant Major Eugenio Espinosa.