[2] In September 2008, Megan Garber of Columbia Journalism Review questioned whether or not Andrea Mitchell should be reporting on the economic downturn, due to possible conflicts of interests.

[6] A June 18, 2012, segment originally aired on MSNBC's Way Too Early with Willie Geist was reaired on Andrea Mitchell Reports and criticized for taking Mitt Romney's comments at a campaign stop in Pennsylvania out of context.

[9][10][11][12] On October 29, 2024, Mitchell announced that she would step down from the program in January 2025 to focus more on her role as an NBC News correspondent.

[13] On March 2, 2009, Savannah Guthrie anchored while Andrea Mitchell was en route to Jerusalem, Israel.

On some occasions when Mitchell is out the show is suspended and MSNBC Live airs in its place featuring rotating anchors.