[6] Since 1983 he has published the writings of the media and culture philosopher Vilém Flusser, whose work he has popularised especially in the German speaking countries.
[8] He initially worked with the moving image, and from the mid-1970s onwards engaged in practical and theoretical approaches to photography, undertaking a project Konstellationen to deal with pictorial syntax.
[9] Müller-Pohle joined the journal Fotografie as writer and critic from 1971 to 1979, when he took over the Swiss Print Letter in 1980,[10][11] including it in European Photography, and has been its publisher ever since.
In 1987, together with Volker Rapsch under their imprint Immantrix they published Flusser's essay "Die Schrift" as an early electronic book on diskette.
Andreas Müller-Pohle's work spans a variety of topics and concepts in pursuit of a reflective examination of the medium of photography.
His first projects from the mid-1970s dealt with questions of image aesthetics and photographic perception, he then turned to - now also with the medium of video - photo recycling and the materiality and immateriality of photography.