His mother, born Ottilie Albrecht, was the daughter of the local Schultheiß (chief municipal administrator).

[2] At the end of 1621 he moved to Leipzig where he lodged with the well connected merchant Georg Winckler in order to study Philosophy and Theology at the university.

He was impeded in his studies by shortage of cash as a result of which he had to support himself with extensive tutoring work, although that provided experience which would also prove of value in his subsequent career.

In 1639 he received and accepted an unsolicited invitation to take up an appointment as rector at the St. John's School in Lüneburg.

[2] Andreas Reyher remained in post at the Ernestium (and as de facto royal education advisor) for the rest of his life.

[4] Reyher's mission in Gotha became the reorganisation of the schools system in the duchy, applying the principals enunciated by education experts of the time including, notably, Wolfgang Ratke.

[2] Another major contribution to advancing the schools system was his development of standardised curricula and his production of text books, many of which were published and distributed far beyond the frontiers of Saxe-Gotha.

[2] Until the eighteenth century the schools system in Saxe-Gotha was the only one of its kind in Germany, and as the appetite for improved educational structures increased it became a template for other German states.

[2] Following the death of his first wife, on 18 January 1659 Andreas Reyher married Anna Blandine Bachoff (1636–1670).

Reyherstrasse ("Reyher Street"), which runs along the north side of the school grounds, was named after him at the same time.