Andrei Istrățescu (born 3 December 1975) is a Romanian chess grandmaster.

He competed in the FIDE World Chess Championship in 1998 and in the FIDE World Cup in 2005 and 2013.

Istrățescu has played for the Romanian national team in the Chess Olympiad, the European Team Chess Championship and the Chess Balkaniads.

[2] In 2004 he finished in second place behind Anatoly Karpov in the rapid knockout tournament in Aix en Provence.

The final score was 6–2 in favour of Karpov.