[2][4][5] Andrei Rădulescu was born in Bucharest, starting his career playing for the junior club Luceafărul București at age 13.
[2][4][6] From 1950 until 1954, Rădulescu played for Rapid București, managing to become the top goalscorer of the 1950 Divizia A season with 18 goals scored in 22 matches.
[2][5][6][7][8] In 1957, Rădulescu became a football referee, arbitrating matches in the Romanian top-division Divizia A and the 1960 Cupa României Final.
[2][4][5][6][12] Andrei Rădulescu played 4 games, scoring 2 goals for Romania, making his debut under coach Iuliu Baratky at the 1948 Balkan Cup in a 3–2 victory against Bulgaria.
[5][13][15][16] Rădulescu's last game for the national team was a friendly which ended with a 6–0 victory against Albania in which he scored two goals.