Andrés Useche is a Colombian American writer, film director, graphic artist, singer-songwriter and activist.

After graduating as a visual designer with emphasis on Film from the Universidad de Caldas, Useche moved to Los Angeles, California to work as a filmmaker, eventually gaining dual citizenship.

Useche wrote, directed, edited, scored and starred in a short film adaptation of his graphic novel Idle Mist on a minuscule $100 budget.

In 2008, in support of Sen. Barack Obama's presidential campaign, Useche volunteered, sang and spoke at rallies and wrote, performed and co-directed in the viral video "Si Se Puede Cambiar", a Spanish language music video also co-directed by Eric Byler and Warren Fu, which debuted on YouTube on February 22, from the group United For Obama.

On April 8, 2008, "Si Se Puede Cambiar" was chosen by YouTube to represent Obama in the first-ever "Trendsetter Tuesday".