[3][4] On September 3, 2016, the Giants waived Adams as part of their final roster cuts, but signed him to their practice squad the following day.

On November 6, 2016, Adams collected a season-high nine combined tackles, deflected two passes, and made his first career interception during a 28–23 win against the Philadelphia Eagles in Week 9.

Adams intercepted a pass by Eagles’ quarterback Carson Wentz, that was initially intended for wide receiver Dorial Green-Beckham, and returned it for a 19-yard gain in the first quarter.

[13] Head coach Ben McAdoo named Adams the backup free safety, behind Darian Thompson, to start the regular season.

[20] In Week 15, Adams collected a season-high seven combined tackles and deflected a pass as the Buccaneers lost 27–20 at the Dallas Cowboys.

[23] In Week 8 against the Tennessee Titans, Adams forced a fumble on Derrick Henry which was recovered by teammate Vernon Hargreaves in the 27–23 loss.

[24] In Week 15 against his former team, the Lions]], Adams recorded his first interception of the season off rookie quarterback David Blough during the 38–17 win.

[27] Adams played in all four games in the Buccaneers' playoff run that resulted in the team winning Super Bowl LV.

[40] Adams returned an interception from quarterback Matt Ryan for his first career defensive touchdown in a 19–10 Week 7 win over the Indianapolis Colts.

[41] On January 2, 2023, Adams was placed on season–ending injured reserve after suffering a torn patellar tendon in Week 17 against the Jacksonville Jaguars.