He has been Member of Parliament (MP) for St Ives in Cornwall since 2024, previously representing the constituency from 1997 to 2015, when he was defeated by the Conservatives' Derek Thomas.

He contested the seat of St Ives at the 1992 general election where he finished second, just 1,645 votes behind the sitting Conservative MP David Harris.

[8] In the House of Commons, George led the Liberal Democrats' Parliamentary DEFRA and Environment team as LibDem Spokesman for agriculture.

[citation needed] George suffers from the autoimmune disease Ankylosing spondylitis and has campaigned for a TNF inhibitor drug treatment to be made available to all patients.

On 12 May 2005, George became the first MP to swear his oath of allegiance to the Queen in Cornish after a long campaign for the language's official recognition.

Local polls commissioned by Penwith District Council indicated that almost 90% of the public were opposed to the formation of the Cornish unitary authority.

[22][23] George opposed the "bedroom tax" in earlier votes, saying that those who supported it "should come down to meet some of my constituents who are affected by it and look them in the eye as they attempt to justify it".

[4] In February 2022 it was announced that George would once again be standing as the Liberal Democrats' candidate for the St Ives constituency at the next general election.