Andrew Wen-Chuan Lo (Chinese: 羅聞全; born 1960) is a Hong Kong-born Taiwanese-American economist and academic who is the Charles E. and Susan T. Harris Professor of Finance at the MIT Sloan School of Management.

Raised by a single mother, Lo graduated from the Bronx High School of Science in 1977.

He is the founder of AlphaSimplex Group,[5] a quantitative investment management company based in Cambridge, Massachusetts, and served as its chairman and chief investment strategist until 2018 when he transitioned to his current role as chairman emeritus and senior advisor.

Lo presented a paper in 2004 at a National Bureau of Economic Research conference, warning of "the rising systematic risk to financial markets and particularly focused on the potential liquidity, leverage and counterparty risk from hedge funds.

His most recent book, Adaptive Markets: Financial Evolution at the Speed of Thought, has also received a number of awards.