Sir Andrew James McMichael, FRS FMedSci KBE (born 8 November 1943) is an immunologist, Professor of Molecular Medicine, and previously Director of the Weatherall Institute of Molecular Medicine at the University of Oxford.
He is particularly known for his work on T cell responses to viral infections such as influenza and HIV.
[1] He went to school at St Pauls and then to the University of Cambridge at Gonville and Caius College to study medicine (1962–1968).
[2] He went on to complete a PhD at the National Institute for Medical Research supervised by 'Ita' Brigitte Askonas and Alan Williamson.
[3] After his PhD McMichael completed his postdoctoral research supervised by Hugh McDevitt at Stanford University.
His research group have created two HIV vaccines which were tested in phase I clinical trials.
[5] McMichael became director of the Weatherall Institute of Molecular Medicine in 2000, and remained so until 2012.
McMichael has supervised over 55 DPhil students over his career,[5] many of whom have gone on to become leading immunologists themselves: In addition McMichael supervised postdoctoral researchers, including Tomáš Hanke (Professor of Vaccine Immunology), and Sarah Rowland-Jones (Professor of Immunology).
[2] McMichael enjoys walking and skiing at his house in La Salle les Alpes, France.
"HLA restriction of cell-mediated lysis of influenza virus-infected human cells".
"The epitopes of influenza nucleoprotein recognized by cytotoxic T lymphocytes can be defined with short synthetic peptides".
Phillips, R. E.; Rowland-Jones, S.; Nixon, D. F.; Gotch, F. M.; Edwards, J. P.; Ogunlesi, A. O.; Elvin, J. G.; Rothbard, J.
"Human immunodeficiency virus genetic variation that can escape cytotoxic T cell recognition".
Altman, J. D.; Moss, P. A.; Goulder, P. J.; Barouch, D. H.; McHeyzer-Williams, M. G.; Bell, J. I.; McMichael, A. J.; Davis, M. M. (4 October 1996).
Goonetilleke, Nilu; Liu, Michael K. P.; Salazar-Gonzalez, Jesus F.; Ferrari, Guido; Giorgi, Elena; Ganusov, Vitaly V.; Keele, Brandon F.; Learn, Gerald H.; Turnbull, Emma L. (8 June 2009).
"The first T cell response to transmitted/founder virus contributes to the control of acute viremia in HIV-1 infection".
Liu, Michael K. P.; Hawkins, Natalie; Ritchie, Adam J.; Ganusov, Vitaly V.; Whale, Victoria; Brackenridge, Simon; Li, Hui; Pavlicek, Jeffrey W.; Cai, Fangping (January 2013).
Fellay, Jacques; Shianna, Kevin V.; Ge, Dongliang; Colombo, Sara; Ledergerber, Bruno; Weale, Mike; Zhang, Kunlin; Gumbs, Curtis; Castagna, Antonella (17 August 2007).
Hill, Adrian V. S.; Allsopp, Catherine E. M.; Kwiatkowski, Dominic; Anstey, Nicholas M.; Twumasi, Patrick; Rowe, Pamela A.; Bennett, Stephen; Brewster, David; McMichael, Andrew J.
"Common West African HLA antigens are associated with protection from severe malaria".
Braud, Veronique M.; Allan, David S. J.; O'Callaghan, Christopher A.; Söderström, Kalle; D'Andrea, Annalisa; Ogg, Graham S.; Lazetic, Sasha; Young, Neil T.; Bell, John I.
Appay, Victor; Dunbar, P. Rod; Callan, Margaret; Klenerman, Paul; Gillespie, Geraldine M.A.
; Papagno, Laura; Ogg, Graham S.; King, Abigail; Lechner, Franziska (2002).
"Memory CD8+ T cells vary in differentiation phenotype in different persistent virus infections".
McMichael, Andrew J.; Borrow, Persephone; Tomaras, Georgia D.; Goonetilleke, Nilu; Haynes, Barton F. (2010).