[8] At 18, he and musician Greg Kurstin formed the short-lived experimental pop band Funkraphiliacs, whereupon he was signed to Capitol Records as a solo artist.

[12][13] After briefly studying at classical conservatory, Wyatt returned to New York City and shortly thereafter formed the group The A.M. with Michael Tighe and Parker Kindred, formerly of Jeff Buckley's band.

[16][17][18] Outside of his own projects, Wyatt has worked extensively with other artists, writing and/or producing songs with Carl Barat,[19][20] Mark Ronson,[21][22][23] Tiggers, Dragons of Zynth, Coco Sumner, and others.

In the documentary Wyatt discussed the challenges of completing the album in only a month, as that was the only time he had between Miike Snow tours and it gave a behind the scenes look at the recording process.

[32] Andrew Wyatt earned the Academy Award for Best Original Song in 2019 for "Shallow", which he co-wrote with Lady Gaga, Mark Ronson and Anthony Rossomando.

[34] On June 29, 2019, Wyatt joined Liam Gallagher onstage at the 2019 Glastonbury Festival, playing guitar on "The River", which he co-wrote with the former Oasis frontman.