At the Rimsky-Korsakov Conservatory in Saint Petersburg, Boreyko studied conducting (with Elisabeta Kudriavtseva and Alexander Dmitriev), graduating summa cum laude.
With the orchestra, Boreyko received awards for the most innovative concert programming in three consecutive seasons from the German Music Critics (Deutscher Musikverleger-Verband).
In May 2008, Boreyko was announced as the next General Music Director of the Düsseldorf Symphony Orchestra, effective with the 2009–2010 season, for an initial contract of 5 years.
[9] He serves as principal guest conductor of the Stuttgart Radio Symphony Orchestra and of the Orquesta Sinfónica de Euskadi.
In April 2013, Boreyko was named the next music director for the Naples Philharmonic, in Florida, as of the 2014–2015 season, his first appointment with an orchestra in the United States.