It is an open, straggling shrub with egg-shaped to oblong leaves with a heart-shaped base, and clusters of 5 to 7 white and dark red flowers.

[2] This species was first formally described in 1863 by George Bentham who gave it the name Commersonia microphylla in Flora Australiensis, from specimens collected by James Drummond near the Murchison River.

[3][4] In 2011, Carolyn Wilkins and Barbara Whitlock transferred the species to Androcalva as A. microphylla in Australian Systematic Botany.

[2] Androcalva microphylla mostly grows in open shrubland between the Murchison River and Eurardy Station in the Geraldton Sandplains and Yalgoo bioregions of south-western Western Australia.

[2][6] Androcalva microphylla is listed as "Priority Two" by the Western Australian Government Department of Biodiversity, Conservation and Attractions,[6] meaning that it is poorly known and from only one or a few locations.