[1] He held a number of political and military positions and was a skilled commander and successfully protected the Eastern Borderlands of the Polish–Lithuanian Commonwealth from the invading armies of Ottoman Turkey, Cossacks and Tatars.

After the abdication of John II Casimir in 1668, he strongly supported the candidacy of the Tsarevich Feodor, for which he was disliked by other nobles.

[2] Potocki later was one of the electors of John III Sobieski, representing the Kiev province in 1674, although he opposed the pro-French and anti-Brandenburgian policies of the king.

In 1683 during an expedition to Vienna, Potocki was nominated as the chief ruler of the Polish–Lithuanian Commonwealth, while Sobieski was absent.

After his death in 1691, Potocki was buried in the city of Stanisławów (named after his father), where he founded a new catholic collegiate church.