Wawrzyk won the European junior title 2006 beating future world champion Ciocan in the semifinal.

On 17 May 2013 he travelled to Russia to challenge for the WBA (regular) heavyweight title held by Alexander Povetkin, and in doing so suffered his first professional loss by third-round TKO.

In September 2016, he defeated former world heavyweight title challenger Albert Sosnowski by sixth-round TKO.

His next professional contest was scheduled for February 2017 against reigning and undefeated WBC heavyweight champion Deontay Wilder in Birmingham, Alabama.

But Wilder was forced to find a new opponent for the next defence of his WBC heavyweight title after Wawrzyk failed a drug test (Stanozolol).