He played college football for the Oregon State Beavers and was selected by the Buffalo Bills in the second round of the 2009 NFL draft.

During his junior year, Levitre started every game at either right or left tackle, and earned Pac-10 Conference second-team honors as selected by the coaches.

For his senior season he was named to the 2008 Outland Trophy watch list, and started all 13 games at left tackle.

He was considered the most-decorated Beaver offensive lineman since John Didion, a consensus All-America choice in the late 1960s.

[11] Counted on to start at left guard, Levitre joined a completely retooled offensive line that was expected to feature two rookie starters—him, and first round pick Eric Wood at right guard—and no players returning at the same position.

[16] In the 2016 season, Levitre and the Falcons reached Super Bowl LI, where they faced the New England Patriots on February 5, 2017.