Angelica Maria Mayolo Obregón (born January 6, 1990) is a Colombian lawyer and politician who is the nation's Minister of Culture.

Alongside her ministerial responsibilities, Obregón is a MLK Scholar in the Environmental Solutions initiative at the Massachusetts Institute of Technology.

[2] She was a graduate student in International and Comparative Law from the University of California, Los Angeles[1] where she held a Critical Race Studies Fellowship.

Two years later, she was made Secretary of Economic Development under the administration of Mayor Norman Maurice Armitage.

She was awarded the Congress of the Republic of Colombia Policarpa Salavarrieta Medal in recognition of her efforts to advance women's rights.