[3] In the United States, the show is available via CBS, syndication and many local stations air the program on their secondary subchannel service to fulfill FCC mandates (at least three hours of E/I related material per week).

The plot is aimed to an older audience and follows a darker storyline, where Raf and Sulfus are killed by Reina and reborn as humans without memories.

The Angels and Devils are required to form pairs as part of their education, each of which will have to deal with a human being, known as Earthly Ones, and help them choose between the right and wrong way in life without being discovered.

While the Angels and Devils are attending their stage on Earth, the planet is threatened by ancient creatures, the Reliveds, led by a mysterious man called Maliki.

The evil Neutral One, Reina, imprisoned in the Limbo with her servant Maliki, wants to take revenge of Angels and Devils who confined her.

Raf discovers that her real father is Maliki, who sacrifices himself to save her, while her mom is imprisoned somewhere in an endless slumber by two warlords.

After the Summer vacations, Angels and Devils return to the Golden School to begin the second year of their stage, their new Earthly Ones are given to them.

The movie focuses on the Angels attending the Summer School at the Sunny College in Alpinville, where Raf hopes she will not meet Sulfus.

Meanwhile, the Earthly ones receive the task of refurbishing the Theatre of Princes (Italian: Teatro dei Principi) and organising a play, Romeo & Juliet by William Shakespeare.

Angel's Friends was distributed all over the world,[17] in countries like Spain, Portugal, Latin America,[18] Belgium, Luxembourg, Bulgaria, Czech Republic, Slovakia, Ex-Yugoslavia.

A second version of the comic, based on the cartoon, was published bimonthly by Preziosi Collection since 2009, in Angel's Friends Magazine.