Pérez is married to former fellow Representative and Senator Liza Fernández Rodríguez, who was appointed by Governor Luis Fortuño in 2012 as a Superior Court Judge.

Pérez won the Special Election for mayor of Guaynabo on August 5, 2017, by a large margin (69.96% to 30.04%) against Senate Majority Leader Carmelo Ríos (NPP).

[5] Some of the irregularities involved Mayor of Guaynabo, Héctor O'Neill, forcing members of the municipal police to vote for Pérez' rival, Antonio Soto.

On December 9, 2021, Pérez was arrested by the Federal Bureau of Investigation (FBI) on corruption charges,[7] and relieved of his duties as mayor of Guaynabo by the Puerto Rico Office of the Special Independent Prosecutor's Panel.

[8] In 2023 he was convicted of corruption[9] following his participation in a scheme involving the awarding of contracts and expediting invoice payments in exchange for thousands of dollars in cash from late 2019 to May 2021.

[11] Pérez has a son, Angel Gabriel, a member of the United States Armed Forces, from a previous marriage.