In film, she is most notable for her roles in Dogtooth, Alps and The Lobster by Yorgos Lanthimos, and A Blast and The Miracle of the Sargasso Sea by Syllas Tzoumerkas.

[2][3] Right after her graduation she collaborated with Greek theatre directors Michail Marmarinos, Lefteris Voyatzis and Yannis Houvardas in various performances, most notably National Anthem'[4]', School of Women, and Romeo and Juliet.

[11] In 2008, Papoulia had the leading part of 'Older Daughter' in Yorgos Lanthimos' Oscar nominated and Cannes film festival awarded Dogtooth.

In 2014, Angeliki Papoulia had the leading part of 'Maria' in Syllas Tzoumerkas' A Blast which premiered at the Locarno International Film Festival.

[12] For her performances in these five films, Angeliki Papoulia was widely praised by the international press,[13][14][15][16][17][18] with Der Spiegel calling her "one of the most fearless European actresses working today'.