Angelo Meli (Italian: [ˈandʒelo ˈmɛːli]; February 10, 1897 – December 1, 1969) was an Italian-American mobster who became a consigliere and then leading Chairman of the Detroit Partnership criminal organization of La Cosa Nostra.

In 1919, in the wake of the Gianola-Vitale War, 'Singing' Sam Catalanotte, Meli, Chester LaMare, and Leo Cellura started the West Side Mob of Hamtramck, Michigan.

In the early 1920s, backed by former Gianola gang member Sam Catalanotte's liquor and vice rackets, Meli, Cellura, and LaMare opened up the Venice Cafe in Detroit.

With Catalanotte's support, Meli formed the Eastside Mob with top aides Leo Cellura, William Tocco, and Joseph Zerilli.

LaMare, on the other hand, was arrested and sentenced to one year in prison amidst the Hamtramck investigations, but was eventually let off with a fine in 1926 for violating Prohibition laws.

After Catalanotte's death on February 14, 1930, LaMare and the West Side Mob began raiding Meli-controlled speakeasies, and liquor storage houses.

It is theorized that Chester LaMare sought to eliminate Meli and Zerrilli as rivals by setting up a phony peace meeting at the Vernor Highway Fish Market on May 31.

According to deputy chief of detectives Robert A. MacPherson, Zerilli claimed that Meli gangsters were not engaging in this warfare, but merely seeking to kill LaMare.

Thomas Licavoli and Frank Cammarata—two of the three suspected trigger-men in the notorious killing of Gerald "Jerry" Buckley on May 31, 1930—were believed to be Meli gangsters.

[16][17] Nick Dellabonte—who, alongside Frank Salimone, was charged with the murder of patrolman Clause Lanstra on June 1, 1930—was the brother-in-law of Angelo Meli.

[16][17] LaMare was to testify against rival gangs of Leo Cellura, William Tocco, Meli, and Zerilli, but he was slain six hours before he was scheduled to appear as a witness in court, on February 7, 1931.

He was considered to be one of the five members of the Ruling Council of the Partnership, along with Joseph Zerilli, Peter Licavoli, Black Bill Tocco, and John Priziola.

Meli had extensive legitimate business holdings in the Michigan area, including a motel, a farm, a trucking company, a gas station, and two different music stores.