Angelo Michele Colonna (21 September 1604 – 1687) was an Italian painter of the Baroque period, active in Bologna, northern and central Italy and Spain.

Also in 1625, along with Ambrogi, he carried out frescoes in the Villa Malvezzi-Campeggi in Bagnarola and after being recommended by Alessandro Tiarini, he helped to decorate the ceiling of the church of Sant'Alessandro in Parma.

In 1625, he collaborated with Lucio Massari, Francesco Gessi and others in the decoration of the Oratory of San Rocco in Bologna, painting six of the saints and allegories.

Together they contributed to the decorations of the Palazzo Spada in Rome, and then painted in the Pitti Palace in Florence, including a large fresco of the 'Fame of the Medici crowned by Glory'.

[1] They became the pre-eminent quadratura fresco painters of northern Italy with Colonna principally executing the figurative elements and Mitelli, the quadratura or illusionistic architectural frameworks: in Modena, they painted in the Este palace at Sassuolo;[2] they executed the ceiling of the now destroyed Oratorio de San Girolamo of Rimini; in 1657 they carried out the decoration of the chapel of the Rosary in the basilica of San Domenico in Bologna, including a framed 'Assumption of the Virgin'; and between 1653 and 1658, they painted the gallery leading to the High Altar of San Michele in Bosco.