The diocese was conceived as a part of the campaign of evangelism that was launched during the tenure of Peter Jasper Akinola as Primate of the Church of Nigeria in 2000.
Emmanuel Afam Ugwu was enthroned on 16 March 2007 at the Cathedral Church of St. Mark, Isu-Awaa as the pioneer Bishop of the new Anglican Missionary Diocese of Awgu/Aninri.
On 9 January 2020, Canon Benson Ndubuisi Chukwunweike was elected the second Bishop of the Diocese at the episcopal retreat in Agbara-Otor.
Benson Chukwunweike was subsequently consecrated on 20 March 2020 at Holy Trinity Cathedral, Lokoja, Kogi State, in a service led by the Primate of the Church of Nigeria, Nicholas D. Okoh.
Benson Ndubuisi Chukwunweike was enthroned on 3 April 2020 at the Cathedral Church of St. Mark, Isu-Awaa as the second bishop of the Anglican Diocese of Awgu/Aninri.