The diocese covers Merseyside north of the River Mersey, south-west Lancashire, western Greater Manchester, and part of northern Cheshire.

Alternative episcopal oversight (for parishes in the diocese who reject the ministry of women priests) is provided by the provincial episcopal visitor (PEV) the Bishop of Beverley, Stephen Race.

He is licensed as an honorary assistant bishop of the diocese in order to facilitate his work there.

On 28 February 2025, it was announced that Ruth Worsley is to become Interim Bishop of Liverpool (i.e. diocesan bishop ad interim) for a period of two years starting later in 2025; to facilitate this role, she is to be translated from Taunton to the vacant suffragan See of Wigan (becoming Bishop of Wigan).

[9] In response, the Diocese of Akure, Nigeria, has indicated that they wish to end their part of the companion link.