The Lords of Anholt, originally liegemen of the Utrecht bishops, reached independence as Freiherren by the early 14th century.

These acquired a comital title and in 1431 had Anholt recognized by King Sigismund of Luxembourg as an imperial estate with a seat in the Reichstag.

In 1512 the forces of Guelders under Duke Charles of Egmond occupied Anholt, as the Bronckhorst counts had sided with his rival Philip I of Castile, and could not be induced to release it until in 1537 they were paid a significant ransom.

The counts stayed loyal to the House of Habsburg, therefore their lordship had to suffer in the Eighty Years' War, when it was attacked by the Geuzen of the Utrecht Union, as well as in the Thirty Years' War.

In 1802, the princes of Salm-Salm, together with their relatives, the princes of Salm-Kyrburg, received the newly created Principality of Salm as a compensation for their losses from the Empire; this much larger new Principality was adjacent to Anholt and eventually incorporated it.