In October 2022, Lorak was sanctioned by the Ukrainian government because she continued to work and live in Russia after the beginning of the Russian invasion of Ukraine in February 2022.

As a child, she listened a lot to Russian singers such as Alla Pugacheva and Larisa Dolina, which were popular at the time she was young.

[13] From the age of six until seventh class, she and her brothers were placed in a foster home in Chernivtsi as her mother was unable to provide for her children full-time.

[16] When the family was given an apartment in Chernivtsi after all, Lorak was subject to severe bullying in her new school due to her poor background.

[19] Kuiek became known as Ani Lorak from March 1995 onwards after she took part in the popular children's music television programme Morning Star on Channel One Russia.

In the summer of 1995, Lorak was one of the laureates of the Chervona Ruta festival, that year held in Sevastopol and Simferopol, which led to her definite breakthrough in the Ukrainian show business.

At the outset of 1999, Lorak started her first extensive and international touring, performing in the United States, France, Germany, Hungary, and in every major city of Ukraine.

She returned to singing completely in Ukrainian again a year later, releasing her fourth album, "Tam, de ty ye...".

[27] In 2005, Ani Lorak made her first attempt to perform at the Eurovision Song Contest and was virtually certain to sing the home country's entry in Kyiv, but ultimately failed to be selected.

Her narrow defeat in the 2005 national pre-selection competition was particularly controversial, given that the winners – GreenJolly – were only added later and did not have to qualify for the final by winning one of the fifteen preliminary heats, unlike all other finalists.

Shortly after the album's release, Lorak ended her contract with Falyosa and started to work with producer Konstantin Meladze.

The song "Shady Lady", written by Karen Kavaleryan and Philipp Kirkorov won the show with a landslide victory.

Lorak, similar to Dmitry Koldun a year prior, held an extensive promo campaign and visited other countries to present her song, including Malta, Russia, Bulgaria, Spain and Germany.

She took second place in the final after Dima Bilan, giving Ukraine its second runner-up position in a row and its third-best score of all-time.

Prior to performing in the final, Lorak had won the Artistic Award, voted the most popular entry among the former winners of the contest.

In October 2009, Lorak was ranked 41st in a top 100 of "most influential women in Ukraine" compiled by experts for the Ukrainian magazine Focus.

[43] Lorak's appearance in the New Year's programme on the television channel Inter was subject to severe criticism on social media.

[47] Meanwhile, Lorak scored large commercial success in Russia, performing several duets alongside singer Grigory Leps, which included "Ukhodi po-angliyski" and "Zerkala," which both fared well in the Russian radio charts.

In 2021, she starred in an episode of the Russia-1 television show Sud’ba cheloveka, in which she gave a rare account into her personal life and career history.

[52] In 2022, she opposed the Russian invasion of Ukraine, but was heavily criticised for her lukewarm and late response and continuation to sing in Russia.

[53][54] In 2005, Ani Lorak and her fiancé Murat opened the Angel Lounge, a restaurant that specializes in Mediterranean cuisine in the center of Kyiv.

In 2005, Lorak was conferred with the St. Stanislav Order of the 4th degree and the Officer's Cross "for strengthening the international authority of Ukraine, for the high professionalism, great creative achievements, charity and adherence to the ideals of chivalry.