Aninoasa (Hungarian: Aninósza or Aninószabányatelep) is a town in Hunedoara County in the Transylvania region of Romania.

It officially became a town in 1989, as a result of the Romanian rural systematization program.

The town is situated near the confluence of both headwater rivers (Jiul de Vest and Jiul de Est) of the Jiu, north of the Vâlcan Mountains and in the eastern foothills of the Retezat Mountains.

The Iscroni train station serves the CFR Line 214, a 17 km (11 mi) railway from Livezeni (in Petroșani) to Lupeni.

Aninoasa is the oldest town in Hunedoara County, being mentioned as far back as 1453 AD.