[2] Born in Kolkata, India and after her mother left her, Forber-Pratt was adopted by Lawrence Pratt and Rosalind Forber when she was two and a half months old.

Raised in Natick, Massachusetts, Forber-Pratt was diagnosed with transverse myelitis when she was four-and-a-half months old; the disorder left her paralyzed from the waist, down.

[7] Her first major international competition was the 2007 Parapan American Games in Rio de Janeiro,[3] where she won two gold medals in the 100-meter and 200-meter races and a bronze in the 400-meter.

[16] In August 2017, Forber-Pratt received the Athletes in Excellence Award from The Foundation for Global Sports Development in recognition of her community service efforts and work with youth.

[17] In 2019, she was featured by the UN Women Global Innovation Coalition for Change as part of the #SheInnovates campaign[18] In 2021, she was appointed by the Biden administration as the Director of the National Institute on Disability, Independent Living, and Rehabilitation Research (NIDILRR).