In The Silmarillion, Ancalagon was described as being one of the more powerful servants of the malevolent being, Morgoth, having been bred to be the fiercest, mightiest, and largest dragon in all of Middle-earth.

[4] However, he later found that the name was already occupied by Ancalagon minor, a Middle Cambrian priapulid worm described in 1977 by Simon Conway Morris.

[2] The strong jaw musculature specialized for up-and-down biting rather than side-to-side grinding movement, and the triangular, laterally compressed premolars and molars with carnassial notches of Ankalagon are typical of mesonychids.

Paleontologists believe that mesonychids would not have been able to slice meat as effectively as other carnivorous animals, but large genera like Ankalagon would have used their pointed teeth to grab a chunk of meat and their unusually strong jaw muscles to pull it free from a large carcass, perhaps bracing it with their front feet.

The evidence of sexual dimorphism in Ankalagon suggests that they formed either permanent social groups (like a pride of lions) or temporary associations (like a lek of grouse) of one male and several females; all living species of Carnivora as well as Primates that show sexual dimorphism in canine size form mating groups of this type.