She visited the United States three times in an effort to avoid the schism created by the views of Elias Hicks.

In 1808, Anna married Isaac Braithwaite (two years earlier, her sister Mary had married Isaac's brother George), thus forging the union of two prominent Quaker dynasties.

[3] Prominent English evangelical Quakers, including Elizabeth Robson, Forster and Braithwaite, travelled to the United States between 1821 and 1827 to denounce Hicks' views.

She visited the United States three times between 1823 and 1827 (the last two journeys accompanied by her husband)[5] and published her Letters and observations relating to the controversy respecting the doctrines of Elias Hicks in 1824.

[6] Hicks felt obliged to respond and in the same year published a letter to his ally in the Philadelphia Meeting, Dr. Edwin Atlee, in The Misrepresentations of Anna Braithwaite.