In around 1728 she married the English actor Henry Giffard who had been acting at Smock Alley for some years.
He had previously been married to Mary Lyddal, probably Anna Marcella's sister, with whom he had two children including William Giffard.
[1] She accompanied her husband to London in 1729 and frequently appeared alongside him over the coming years.
She made her British debut at the Goodman's Fields Theatre, and this became a base for the couple after Henry took over management of the company and attempted to turn it into the third major London theatre, despite operation without a patent.
[2] Her sister Sarah Hamilton was also an actress who worked extensively on the Irish and British stage.