She and her brothers were educated by her father in his trade, and active as the assistants in his studio as children.

They were all assigned to assist him when he was commissioned by Olof Rudbeck (1630–1702) to illustrate his four volumes work Atlantica (Atland eller Manheim) and Campus Elysii.

She performed commissions of illustrations by method of drawing, chalcography, copper engraving, India ink and woodcut.

Among her many commissions were woodcut for the paper Posttidningen, chalcography for prayer books and, in collaboration with her brother Philip, India ink for the illustration of weapons.

In 1710, Anna Maria Thelott became one of the many victims of the 1710–1713 plague of Sweden, and died in Stockholm at the age of twenty-seven.