[5] She was selected for the German team at the 2010 Winter Paralympics held in Vancouver, British Columbia, Canada where she competed in four events.

She won the bronze medal in the super-G finishing behind Claudia Lösch of Austria and American Alana Nichols in a time of 1 minute 38.25 seconds.

[5][10][11] Competing in the slalom she was initially disqualified for not having her outriggers in a stationary position at the start of her first run and compatriot Anna-Lena Forster was identified as the gold medal winner in press releases.

[5][14] Schaffelhuber won a fourth gold medal in the combined, with Forster again taking silver as the two German skiers were the only athletes to complete the race.

[15][16][17] She won her fifth gold medal, completing a clean sweep in the sitting events, by winning the giant slalom in a combined time of 2 minutes 51.26 seconds.