She was friend to other important writers of the time, such as D. H. Lawrence, George Bernard Shaw, Katherine Mansfield and Dylan Thomas.
She is remembered as a modernist figure and feminist writer, one who did not command sustained critical attention in her lifetime, though her poetry did earn her a major reputation at the time of writing and had been frequently anthologised.
Wickham's literary reputation has improved since her death and she is now regarded as an important early 20th-century woman writer.
Wickham returned to London in 1904, where she took singing lessons and won a drama scholarship (at the future RADA, just founded).
Wickham became involved in the contemporary philanthropic movement concerned with maternal care, at St Pancras Hospital.
According to Jennifer Vaughan Jones, the crisis was specifically precipitated by a poem Wickham had relayed to Hepburn, entitled "Nervous Prostration", which includes the lines: I married a man of the Croydon class When I was twenty-two.
Given the complexities of Wickham's emotional life at the time, including having birthed four children and suffered two miscarriages, along with domestic conflicts with her husband, there may have been other factors at play.
During World War I Wickham met the poet and publishing impresario Harold Monro at his Poetry Bookshop.
[2] During the 1930s she was well-known in literary London, and wrote a great deal of poetry (much of which was later lost in war damage) and much of which remained unpublished.