From 1999 to 2008, Newitz wrote a syndicated weekly column called Techsploitation, and from 2000 to 2004 was the culture editor of the San Francisco Bay Guardian.

From 2008 to 2015, Newitz was editor-in-chief of Gawker-owned media venture io9, and subsequently its direct descendant Gizmodo, Gawker's design and technology blog.

[7] Newitz was awarded a Knight Science Journalism Fellowship for 2002 to 2003, supporting them as a research fellow at Massachusetts Institute of Technology.

[8] From 2004 to 2005 Newitz was a policy analyst for the Electronic Frontier Foundation, and from 2007 to 2009 was on the board of Computer Professionals for Social Responsibility.

Newitz's second novel, The Future of Another Timeline, published in 2019, was described on their website as: "[...] about time travel and what it would be like to meet yourself as a teenager and have a really, really intense conversation with her about how fucked up your high school friends are.

They have also written for publications including Wired, Popular Science, The New Yorker, The Atlantic, Slate, The Washington Post, Smithsonian, and more.

[1] Newitz's work has been published in Popular Science, Wired, Salon.com, New Scientist, Metro Silicon Valley,[36] the San Francisco Bay Guardian,[25] and at AlterNet.