Emergency services at Annandale-on-Hudson are provided by the municipal Red Hook Police Department, the Dutchess County Sheriff's Office, New York State Police, Red Hook Volunteer Fire Company, and Tivoli Volunteer Fire Company.

The Munsee and Muhheaconneok people were the original inhabitants of this area and, due to forced migration, now reside in Northeast Wisconsin and are known as the Stockbridge-Munsee Community.

[2] The town takes its name from an estate donated by John Bard and his wife to Columbia University so that a college could be formed there.

There are also a few private residences, small businesses, and undeveloped land controlled by the New York State Department of Environmental Conservation.

[5] Bard College's resident archaeologist Christopher Lindner has extensively researched the history of this area.