On 11 June 1874, Lady Anne was married to James Henry Robert Innes-Ker, Marquess of Bowmont and Cessford, eldest son of the sixth Duke of Roxburghe.

[5] In 1883, she was appointed Mistress of the Robes to Queen Victoria by the Liberal Prime Minister William Ewart Gladstone, and served in that capacity until 1885.

In 1892, when Gladstone again came to power, his policy of Home Rule for Ireland had alienated many of the upper classes, and no lady of ducal rank could be found who was willing to serve as Mistress of the Robes.

[citation needed] In 1906 she christened the newest and largest ship then in the world, the Cunard Line's RMS Mauretania.

[8] She died in 1923 in London, at the home of her daughter Lady Evelyn and her husband, Colonel William Collins, after a lengthy illness.