She corresponded with other activists and died of the plague in the same year as her husband, John Hooper became a Protestant martyr.
Hooper was born in the Flemish Region and she and her sister, not her parents or brother, became Protestants.
By this time her father had died and her brother took the unopened letter from his mother and burnt it.
He was called to account on 22 January 1555 by the Bishop of Winchester and one of the first demands of Hooper was that he renounced his wife.
Anne wrote her last extant letter to Bullinger asking him to publish one of her husbands writings.