She was Member of the Riksdag, representing her home constituency of Jönköping County, from 2006 to 2023, and leader of the Centre Party from September 2011 to February 2023.

[2] During her last year at Finnvedens Secondary School in Värnamo, where she studied social sciences, she developed an interest in politics.

During the 2002 general election she was employed as an election agent for the party's youth organization (CUF) in Jönköping County and in the same year she won a Dag Hammarskjöld Scholarship, which gave her the chance to immerse herself in international peace and environmental issues at the UN Headquarters in New York.

[5] In January 2007, together with her colleague Fredrick Federley, Lööf initiated the Liberal Group, a network of liberal-minded people both inside and outside the Riksdag.

[citation needed] In 2008 Lööf was awarded the "Young European Leadership Program" grant from the United States Embassy.

Until 2008 Lööf was a substitute to the Nordic Council's Swedish delegation, and the pre-term in office she worked for the Committee on the Constitution as a member.

[9] The speech also drew attention because of the caustic review by Social Democrat former minister of culture Marita Ulvskog: "New speechwriter for Annie Lööf?

In 2017, Annie Lööf had the highest trust figures of any major political party leader in Sweden by Swedish voters.

[16][17] Following the inconclusive elections in 2018, the speaker of Sweden’s parliament Andreas Norlén asked Lööf to explore the possibility of forming a new government.

[18] Löof subsequently tried to build support for a broad government which excluded the Sweden Democrats and the Left Party and kept intact the centre-right Alliance, a four-party bloc of which the Center is part.

[20] In January 2019, she eventually led her party to abandon its traditional center-right allies and back Social Democrat leader Stefan Löfven as Prime Minister.