[4] Annopol received town rights in 1761, lost them in 1870[citation needed] and regained on 1 January 1996.

Following the German-Soviet invasion of Poland, which started World War II in 1939, Annopol was occupied by Germany until 1944.

Jews from nearby villages and smaller towns, as well as from Kalisz and Łódź, were displaced to the Annopol ghetto.

[9] The history of Annopol is inextricably linked to that of Annopol-Rachów village close by, often combined as one and the same in written records.

Annopol does not have a rail station, but the town is placed along national road 74, which goes from Piotrków Trybunalski to the Ukrainian border at the village of Zosin.