She is more commercially known for her leading role as Catherine Beaumont in the TF1 hit series Une famille formidable which ran for 15 seasons (1992-2018) regularly topping national primetime viewership numbers and also broadcast throughout French-speaking Europe peaking at 11 million viewers in France alone.

[24] Her trapeze number for the Gala de l'Union des artistes [fr] with Francis Perrin[25] as well as her 'red dress scene' with Jean Rochefort swaying her hips as a nod to Marilyn Monroe on Vladimir Cosma's original score both became cult in French popular culture.

She lost her parents, Lucien and Ginette Legras who were both photographers, at the age of 8[34] as they accidentally died on 6 November 1955 in Sotteville-lès-Rouen poisoned by carbon monoxide in their bathroom due to a faulty gas water heater and insufficient ventilation.

She started out as a model and took her first steps on stage in 1965, playing in La Mamma by André Roussin[38] and made her screen debut in Jean-Luc Godard's Two or Three Things I Know About Her (1967).

Anny Duperey was nominated for the 1977 César Award for Best Actress in a Supporting Role for her performance in "Un éléphant ça trompe énormément" (An Elephant Can Be Extremely Deceptive).